| 发明名称 |
BISPECIFIC NANOBODIES AS A THERAPEUTIC FOR ALZHEIMER'S DISEASE |
| 摘要 |
The present invention provides for the treatment of Alzheimer's disease. More specifically, a recombinant bispecific antibody fragment that simultaneously blocks beta-secretase activity while also promoting alpha-secretase activity, comprising a first portion and a second portion, wherein the first portion blocks beta secretase activity and the second portion promotes alpha-secretase activity. |
| 申请公布号 |
US2012230999(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
US201013395011 |
申请日期 |
2010.09.08 |
| 申请人 |
SIERKS MICHAEL;BODDAPATI SHANTA;KASTURIRANGAN SRINATH;ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THESTATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZ |
发明人 |
SIERKS MICHAEL;BODDAPATI SHANTA;KASTURIRANGAN SRINATH |
| 分类号 |
A61K39/395;A61P25/28;C07K16/40;C12N5/02;C12N5/071;C12N5/079 |
主分类号 |
A61K39/395 |
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