Stable non-aqueous pharmaceutical compositions

摘要

The present invention relates to shelf stable non-aqueous pharmaceutical compositions, and to the use thereof in methods of treating diabetes and hyperglycaemia. The composition comprises a dehydrated therapeutically active insulinotropic peptide, and at least one semi-polar protic organic solvent which insulinotropic peptide has been dehydrated at target pH which is at least 1pH unit from the pI of the peptide in aqueous solution.