发明名称 IDENTIFICATION OF LKB1 MUTATION AS A PREDICTIVE BIOMARKER FOR SENSITIVITY TO TOR KINASE INHIBITORS.
摘要 Provided herein are methods for treating and/or preventing a cancer or a tumor syndrome in a patient, comprising administering an effective amount of a TOR kinase inhibitor to a patient having cancer or a tumor syndrome, characterized by a LKB 1 and/or AMPK gene or protein loss or mutation.
申请公布号 MX2012009030(A) 申请公布日期 2012.09.12
申请号 MX20120009030 申请日期 2011.02.03
申请人 SIGNAL PHARMACEUTICALS, LLC 发明人 SABITA SANKAR;WEIMING XU;RAJESH CHOPRA;YUHONG NING;SHUICHAN XU
分类号 A61K31/497 主分类号 A61K31/497
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