发明名称 |
IDENTIFICATION OF LKB1 MUTATION AS A PREDICTIVE BIOMARKER FOR SENSITIVITY TO TOR KINASE INHIBITORS. |
摘要 |
Provided herein are methods for treating and/or preventing a cancer or a tumor syndrome in a patient, comprising administering an effective amount of a TOR kinase inhibitor to a patient having cancer or a tumor syndrome, characterized by a LKB 1 and/or AMPK gene or protein loss or mutation. |
申请公布号 |
MX2012009030(A) |
申请公布日期 |
2012.09.12 |
申请号 |
MX20120009030 |
申请日期 |
2011.02.03 |
申请人 |
SIGNAL PHARMACEUTICALS, LLC |
发明人 |
SABITA SANKAR;WEIMING XU;RAJESH CHOPRA;YUHONG NING;SHUICHAN XU |
分类号 |
A61K31/497 |
主分类号 |
A61K31/497 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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