发明名称 Fused-ring derivative and medical application of same
摘要 The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal plasma uric acid level and the like. The present invention relates to fused ring derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of plasma uric acid level, prodrugs thereof, salts thereof or the like. In the formula (I), X1 and X2 represent CH or N; ring U represents aryl or heteroaryl; m represents integral number from 0 to 2; n represents integral number from 0 to 3; R1 represents a hydroxy group, amino or C1-6 alkyl; R2 represents C1-6 alkyl, C1-6 alkoxy C1-6 alkyl or the like.
申请公布号 US8263622(B2) 申请公布日期 2012.09.11
申请号 US200913124345 申请日期 2009.10.14
申请人 SHIMIZU KAZUO;IIZUKA MASATO;FUJIKURA HIDEKI;TAKIGAWA YASUSHI;HIRATOCHI MASAHIRO;KISSEI PHARMACEUTICAL CO., LTD. 发明人 SHIMIZU KAZUO;IIZUKA MASATO;FUJIKURA HIDEKI;TAKIGAWA YASUSHI;HIRATOCHI MASAHIRO
分类号 A61K31/426;A61K31/433;A61K31/4709;A61K31/4725;C07D215/16;C07D239/72;C07D277/24 主分类号 A61K31/426
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