| 发明名称 |
METHODS AND MATERIALS FOR GENERATING SH3 DOMAINS WITH TAILORED BINDING PROPERTIES |
| 摘要 |
The present invention relates to controlled modification of Src homology region 3 (SH3) domains by using random manipulation of the non-conserved region of SH3 RT-loop. Consequently, the invention concerns methods and materials for generating SH3 domains with engineered binding properties, and their use as tools in research, diagnostics, therapy and drug discovery.
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| 申请公布号 |
CA2374180(C) |
申请公布日期 |
2012.09.11 |
| 申请号 |
CA20002374180 |
申请日期 |
2000.05.26 |
| 申请人 |
SAKSELA, KALLE |
发明人 |
HIIPAKKA, MARITA;SAKSELA, KALLE |
| 分类号 |
C12N15/10;G01N33/50;A61K38/00;A61K38/16;A61K38/45;A61K48/00;A61P43/00;C07K14/16;C07K14/47;C12N15/09;G01N33/53;G01N33/566 |
主分类号 |
C12N15/10 |
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