发明名称 |
Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells |
摘要 |
The present invention is directed to a method of separating oligodendrocyte cells or progenitor cells thereof from a mixed population of cells. It comprises selecting a promoter which functions only in the oligodendrocyte cells or progenitor cells thereof, introducing a nucleic acid molecule encoding a fluorescent protein under control of that promoter into the mixed population cells, allowing the oligodendrocyte cells or progenitor cells thereof to express the fluorescent protein, and separating the fluorescent cells from the mixed population cells, where the separated cells are the oligodendrocyte cells or progenitor cells thereof. The invention also relates to the isolated and enriched human oligodendrocyte cells or progenitor cells thereof. |
申请公布号 |
US8263402(B1) |
申请公布日期 |
2012.09.11 |
申请号 |
US19990282239 |
申请日期 |
1999.03.31 |
申请人 |
GOLDMAN STEVEN A.;WANG SU;CORNELL RESEARCH FOUNDATION, INC. |
发明人 |
GOLDMAN STEVEN A.;WANG SU |
分类号 |
C12N5/02;A61K35/12;A61P25/00;C12N5/071;C12N5/079;C12N5/0797 |
主分类号 |
C12N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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