发明名称 Dual alanyl aminopeptidase and dipeptidyl peptidase iv inhibitors for functionally influencing different cells and for treating immunological inflammatory, neuronal and other diseases
摘要 The present invention relates to substances capable of specifically inhibiting Ala-p-nitroanilide-cleaving peptidases and Gly-Pro-p-nitroanilide-cleaving peptidases as well, for a use in the medical field. Furthermore, the invention relates to the use of at least one of such substances or of at least one pharmaceutical or cosmetic composition containing at least one such substance for a prophylaxis or a therapy of diseases, particularly for a prophylaxis and a therapy of diseases accompanied by an excessive immune response (autoimmune diseases, allergies, transplant rejections), of other chronic-inflammatory diseases, of neuronal diseases and cerebral damage, of skin diseases (inter alia acne, psoriasis), of tumor diseases and of specific virus infections (inter alia SARS).
申请公布号 US8263636(B2) 申请公布日期 2012.09.11
申请号 US20040575878 申请日期 2004.10.15
申请人 ANSORGE SIEGFRIED;BANK UTE;NORDHOFF KARSTEN;TAEGER MICHAEL;STRIGGOW FRANK;IMTM GMBH;KEYNEUROTEK PHARMACEUTICALS AG 发明人 ANSORGE SIEGFRIED;BANK UTE;NORDHOFF KARSTEN;TAEGER MICHAEL;STRIGGOW FRANK
分类号 A61K31/4045;A61K31/404;C07C233/83;C07C243/28;C07C251/86;C07C327/48;C07D207/327;C07D209/08;C07D295/15;C07D307/52;C07D317/58;C07D403/06;C07D405/06;C07D513/04 主分类号 A61K31/4045
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