摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to organic chemistry and specifically an improved method of producing 3, 28-hydroxylupane of formula I: ^ . ^ The method involves reduction of 3, 28-dihydroxy-20(29)-lupene to 3, 28-dihydroxylupane with diborane obtained in situ, with molar ratio 3, 28-dihydroxy-20(29)-lupene:diborane equal to 1:5, in tetrahydrofuran at temperature 65C for 4 hours. ^ EFFECT: output of the end product is equal to 78%. ^ 1 cl, 1 ex |