摘要 |
FIELD: medicine. ^ SUBSTANCE: present invention refers to immunology. What is contemplated is an antibody which specifically binds sphingosine-1-phosphate (S1P), and its antigen-binding fragment. There are presented a pharmaceutical composition, an antibody expression vector, a host cell, as well as a method of treating an S1P-related disease or disorder. ^ EFFECT: use of the invention can find further application in treating various S1P-related diseases. ^ 17 cl, 26 ex, 11 tbl, 13 dwg |