发明名称 |
COMBINATION DOSAGE FORM CONTAINING A TAMSULOSIN AND TESTOSTERONE-5a-REDUCTASE INHIBITOR |
摘要 |
The invention relates to a population of tamsulosin-comprising pellets for oral administration of a combination dosage form containing physically separated a tamsulosin dose in the form of the population of the tamsulosin comprising pellets and at least one other dose of a pharmaceutically active substance, said pellets comprising tamsulosin hydrochloride uniformly dispersed in a carrier matrix, wherein (i) said pellets in the population have a size of less than about and, advantageously, at least 90 % of the pellets have a size of larger than ; and (ii) an average content of tamsulosin hydrochloride in the population of pellets is between about 0.15-3.00 weight percent, calculated on a dry pellet basis, to a process of making such population of pellets, and to their use. |
申请公布号 |
UA99678(C2) |
申请公布日期 |
2012.09.10 |
申请号 |
UA20110007271 |
申请日期 |
2008.12.09 |
申请人 |
SYNTHON B.V. |
发明人 |
VAN DEN HEUVEL, DENNIE, JOHAN, MARIJN;WEIJERS, JOHANNES, WILHELMUS, MAURICE;PAMPERIN, DIRK |
分类号 |
A61K9/50;A61K9/48;A61K31/18;A61K31/58;A61P13/08 |
主分类号 |
A61K9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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