发明名称 |
PDGFRb-SPECIFIC INHIBITORS |
摘要 |
The invention is directed to novel PDGFR&bgr;-specific antagonists. The antagonists include antibodies, which can be bispecific. The antibodies are used to reduce or inhibit tumor growth and or to treat an angiogenic disease. The invention also includes combinations of PDGFR&bgr;-specific antagonists with VEGFR antagonists for such treatments. The antagonists can further be administered in combination with other anti-angiogenic or anti-neoplastic drugs. |
申请公布号 |
UA99608(C2) |
申请公布日期 |
2012.09.10 |
申请号 |
UA20090010244 |
申请日期 |
2008.04.17 |
申请人 |
IMCLONE LLC |
发明人 |
ZHU, ZHENPING;SHEN, JUQUN |
分类号 |
C07K16/28;A61K39/395;C12N15/13 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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