发明名称 |
GPR119 AGONIST |
摘要 |
<p>A compound represented by general formula (I), said compound being a GPR119 agonist, or a salt thereof which is usable as an antidiabetic drug. In general formula (I): one of T1, T2, T3 and T4 represents N and the remainder three represent CR5, or T1, T2, T3 and T4 all represent CR5; R5 represents H, a halogen atom, a C1-8 alkyl group, a C1-8 alkylsulfonyl group, a 5- or 6-membered heteroaryl group or the like; R3 and R4 represent H or a C1-8 alkyl group; --- represents a single or double bond; A represents (CH2)m or the like; X and Y represent an optionally substituted C1-3 alkylene group; Z represents C(O)OR6, an optionally substituted 5- or 6-membered heteroaryl group or the like; and R1 and R2 represent H, a halogen atom or the like.</p> |
申请公布号 |
WO2012117996(A1) |
申请公布日期 |
2012.09.07 |
申请号 |
WO2012JP54721 |
申请日期 |
2012.02.27 |
申请人 |
NIPPON CHEMIPHAR CO., LTD.;ENDO, TSUYOSHI;TAKAHASHI, RIE;KANAKUBO, NORIKO;TAKAHASHI, TOSHIHIRO;KUNIGAMI, TOSHIHIRO |
发明人 |
ENDO, TSUYOSHI;TAKAHASHI, RIE;KANAKUBO, NORIKO;TAKAHASHI, TOSHIHIRO;KUNIGAMI, TOSHIHIRO |
分类号 |
C07D401/14;A61K31/4545;A61K31/497;A61K31/506;A61P3/10;A61P43/00;C07D413/14;C07D471/04 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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