发明名称 |
LUNG CANCER-RELEVANT HUMAN EMBRYONIC STEM CELL SIGNATURE |
摘要 |
The invention provides a method of detecting cancer, a progression of cancer, or a predisposition to cancer in a human, comprising (a) obtaining a sample of airway basal cells from the human, and (b) analyzing the sample to determine expression of one or more hESC-signature genes, wherein the expression or lack of expression of the one or more hESC-signature genes is indicative of a presence or absence of cancer, a progression of cancer, or a predisposition to cancer in the human. The invention also provides an in vitro model for lung cancer, comprising airway basal cells that express one or more hESC-signature genes. |
申请公布号 |
WO2012119150(A2) |
申请公布日期 |
2012.09.07 |
申请号 |
WO2012US27744 |
申请日期 |
2012.03.05 |
申请人 |
CORNELL UNIVERSITY;CRYSTAL, RONALD, G.;SHAYKHIEV, RENAT |
发明人 |
CRYSTAL, RONALD, G.;SHAYKHIEV, RENAT |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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