发明名称 |
DISPLAY OF DISULFIDE LINKED DIMERIC PROTEINS IN FILAMENTOUS PHAGE |
摘要 |
Methods are provided for the display of a complex homodimer protein on the surface of a bacteriophage particle and combinatorial synthetic libraries of such proteins displayed as a fusion polypeptide with filamentous phage pIX coat protein. Heterodimeric or more complex interchain bonded structure, such as disulfide-linked, multimeric proteins, may be displayed using the method of the invention.
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申请公布号 |
US2012225085(A1) |
申请公布日期 |
2012.09.06 |
申请号 |
US201013509292 |
申请日期 |
2010.11.15 |
申请人 |
HUANG CHICHI;SPINKA-DOMS TRACY;FRANSSON JOHAN |
发明人 |
HUANG CHICHI;SPINKA-DOMS TRACY;FRANSSON JOHAN |
分类号 |
A61K39/395;C07K14/00;C07K16/28;C12N1/21;C12N15/13;C12N15/63;C40B30/06;C40B40/02;C40B50/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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