摘要 |
The present invention is directed to Buprenorphine Analog compounds of the Formula I, Formula II or Formula III shown below, wherein R, R, R, R, R, R, X, Z and Y are as defined herein., R1 H3CO (I) OCH3 OCH3 (III) Compounds of the Invention are useful for treating pain and other conditions modulated by activity of opioid and ORLl receptors. |