Simultaneous determination of aneuploidy and fetal fraction
摘要
The invention provides compositions and methods for simultaneously determining the presence or absence of fetal aneuploidy and the relative amount of fetal nucleic acids in a sample obtained form a pregnant female. The method encompasses the use of sequencing technologies and exploits the occurrence of polymorphisms to provide a streamlined noninvasive process applicable to the practice of prenatal diagnostics.
申请公布号
AU2010343278(A1)
申请公布日期
2012.09.06
申请号
AU20100343278
申请日期
2010.12.01
申请人
VERINATA HEALTH, INC.
发明人
QUAKE, STEPHEN;RAVA, RICHARD P.;CHINNAPPA, MANJULA;COMSTOCK, DAVID A.;HEILEK, GABRIELLE