发明名称 |
ANTIMICROBIAL AND RADIOPROTECTIVE COMPOUNDS |
摘要 |
Disclosed is a method of treatment and/or prophylaxis of a microbial infection, employing compounds of formula (I), in which X and Y are either the same of different and selected from a hereroatiom; is a double or single bond depending on the heteroatoms X and Y; R1 to R5 are either the same or different and selected from hydrogen or a non-deleterious substituent; and R6 to R7 are either the same or different and selected from hydrogen and a non-deleterious substituent or one of R6 to R7 are absent when there is a double bond present. Also disclosed are methods for protecting a subject from radiation damage, methods of cancer radiotherapy, and use of the disclosed compounds as an antimicrobial or radioprotective agent. |
申请公布号 |
US2012225935(A1) |
申请公布日期 |
2012.09.06 |
申请号 |
US201213425054 |
申请日期 |
2012.03.20 |
申请人 |
DENISENKO PETER PROKOFIEVICH;SAPRONOV NIKOLAY SERGEEVICH;TARASENKO ALEXANDER ALEXANDROVICH;BIODIEM LTD. |
发明人 |
DENISENKO PETER PROKOFIEVICH;SAPRONOV NIKOLAY SERGEEVICH;TARASENKO ALEXANDER ALEXANDROVICH |
分类号 |
A61K31/357;A61K31/36;A61K31/4184;A61K31/423;A61P31/00;A61P31/02;A61P31/04;A61P31/06;A61P31/08;A61P31/10;A61P31/12;A61P33/02;A61P39/00;C07D235/06;C07D235/08;C07D263/56;C07D317/52 |
主分类号 |
A61K31/357 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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