发明名称 BRIDGED PIPERIDINE DERIVATIVES
摘要 The present invention relates to compounds of formula I hetaryl I, hetaryl II, R1, R2, R3, Y, m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of &bgr;-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
申请公布号 US2012225884(A1) 申请公布日期 2012.09.06
申请号 US201213405404 申请日期 2012.02.27
申请人 BAUMANN KARLHEINZ;GREEN LUKE;LIMBERG ANJA;LUEBBERS THOMAS;THOMAS ANDREW 发明人 BAUMANN KARLHEINZ;GREEN LUKE;LIMBERG ANJA;LUEBBERS THOMAS;THOMAS ANDREW
分类号 A61K31/4985;A61K31/437;A61K31/444;A61K31/506;A61K31/519;A61P25/00;A61P25/28;C07D451/04;C07D471/04;C07D487/04 主分类号 A61K31/4985
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