发明名称 |
ADAM12 Inhibitors and Their Use Against Inflammation-Induced Fibrosis |
摘要 |
The present invention relates to the field of fibrosis and inflammation and more particularly to the use of ADAM12 (A Disintegrin and Metalloproteinase 12) inhibitors to prevent or treat inflammation-induced fibrosis. The present invention also relates to the use of ADAM12 as a marker for inflammation-induced fibrosis and to the ablation of ADAM12 expressing cells as therapeutic approach to interfere with the development of pro-fibrotic cells.
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申请公布号 |
US2012225082(A1) |
申请公布日期 |
2012.09.06 |
申请号 |
US201013393113 |
申请日期 |
2010.08.27 |
申请人 |
PEDUTO LUCIE;EBERL GERARD |
发明人 |
PEDUTO LUCIE;EBERL GERARD |
分类号 |
A61K39/395;A01K67/027;A61K38/02;A61K38/43;A61K48/00;A61P29/00;A61P43/00;C07H21/02;C07K19/00;C12N1/21;C12Q1/68 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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