发明名称 |
IMPROVED NEURTURIN MOLECULES |
摘要 |
<p>Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.</p> |
申请公布号 |
EP2493918(A2) |
申请公布日期 |
2012.09.05 |
申请号 |
EP20100827453 |
申请日期 |
2010.10.28 |
申请人 |
CNS THERAPEUTICS, INC.;UNIVERSITY OF HELSINKI |
发明人 |
PENN, RICHARD;RUNEBERG-ROOS, PIA;BESPALOV, MAXIM;SAARMA, MART |
分类号 |
C07K14/47;A61K38/17;A61P25/00;C07K14/475 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|