发明名称 |
METHOD FOR PRODUCING ANTIGEN-SPECIFIC B CELL POPULATION |
摘要 |
<p>The present invention provides a method for producing an antigen-specific B cell population comprising IgG-positive B cells specific to a specific antigen, the method comprising: culturing IgG-positive B cells together with the specific antigen in the presence of IL-21, while conferring stimulation to the IgG-positive B cells via CD40, a BAFF receptor and Fas; and screening for antigen-specific B cells specific to the specific antigen to obtain an antigen-specific B cell population comprising the IgG-positive B cells specific to the specific antigen.</p> |
申请公布号 |
EP2495312(A1) |
申请公布日期 |
2012.09.05 |
申请号 |
EP20100826677 |
申请日期 |
2010.10.25 |
申请人 |
TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION |
发明人 |
KITAMURA, DAISUKE;NOJIMA, TAKUYA |
分类号 |
C12N5/0781;C12P21/08 |
主分类号 |
C12N5/0781 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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