| 摘要 |
The invention describes a method for identifying a compound capable of inhibiting infection by HIV, comprising contacting a HIV CA polypeptide with a CPSF6 polypeptide in the presence of the compound, and determining the influence of the compound on the binding of HIV CA to CPSF6, by measuring the interaction of CPSF6 with HIV CA at one or more of residues 53, 56-57, 66-67, 70, 73-74, 105, 7, 109 and 130 thereof. |
