The present invention provides methods of detecting mutations in a GNA11 gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated GNA11 gene.
申请公布号
EP2494072(A1)
申请公布日期
2012.09.05
申请号
EP20100777166
申请日期
2010.10.29
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;THE UNIVERSITY OF BRITISH COLUMBIA;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人
BASTIAN, BORIS C.;VAN RAAMSDONK, CATHERINE D.;BARSH, GREGORY S.
