IMPROVED VACCINES AGAINST BORDETELLA PERTUSSIS BASED ON LPS GLYCOSYLTRANSFERASE MUTANTS
摘要
The invention relates to an improved vaccine against pertussis wherein mutants of Bordetella pertussis having a modified LPS molecule or the obtainable LPS molecules are used. These mutants or the obtainable LPS molecules may further be used as an adjuvant.
申请公布号
EP2134743(B1)
申请公布日期
2012.09.05
申请号
EP20080723920
申请日期
2008.03.25
申请人
DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS
发明人
GEURTSEN, JEROEN JOHANNES GERARDUS;TOMMASSEN, JOHANNES PETRUS MARIA;VAN DER LEY, PETER ANDRE
