发明名称 |
Method for the production of α, ω-olefins by using the copper catalyzed coupling reaction of a Grignard reagent with an allylic substrate |
摘要 |
A process for the synthesis of linear α,ω-diolefins from an allylic substrate comprises the steps of a) forming the bis-Grignard reagent XMgCH2(CH2)nCH2MgX from an α,ω-acyclic dihalide with X being a halogen; b) preparing a solution comprising an allylic substrate and a copper catalyst; c) catalyzing a coupling reaction by adding to the solution of step (b) the bis-Grignard reagent of step (a); and d) isolating and purifying the α,ω-olefin coupling reaction product. |
申请公布号 |
US8258362(B2) |
申请公布日期 |
2012.09.04 |
申请号 |
US20100773458 |
申请日期 |
2010.05.04 |
申请人 |
NACHARAJU KRISHNAMURTHY;TAYLOR PAUL D.;COONEY MARK J.;CRABTREE LARRY A.;ISP INVESTMENTS INC. |
发明人 |
NACHARAJU KRISHNAMURTHY;TAYLOR PAUL D.;COONEY MARK J.;CRABTREE LARRY A. |
分类号 |
C07C2/76 |
主分类号 |
C07C2/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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