发明名称 |
Interferon-antibody fusion proteins demonstrating potent apoptotic and anti-tumor activities |
摘要 |
Novel chimeric moieties that show significant efficacy against cancers are provided. In certain embodiments the chimeric moieties comprise a targeting moiety attached to an interferon. In certain embodiments, the chimeric moieties comprise fusion proteins where an antibody that specifically binds to a cancer marker is fused to interferon alpha (IFN-α) or interferon beta (IFN-β). |
申请公布号 |
US8258263(B2) |
申请公布日期 |
2012.09.04 |
申请号 |
US20090650329 |
申请日期 |
2009.12.30 |
申请人 |
MORRISON SHERIE L.;HUANG TZU-HSUAN;XUAN CAIYUN;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MORRISON SHERIE L.;HUANG TZU-HSUAN;XUAN CAIYUN |
分类号 |
A61K38/21;A61K39/00;A61K39/395;C07K14/555;C07K16/00;C07K16/30;C07K16/46;C12P21/00 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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