发明名称 TOLEROGENIC PEPTIDES FROM MYELIN BASIC PROTEIN
摘要 There is provided a peptide that is capable of binding to an MHC class I or II molecule without further processing (i.e., an apitope), which comprises a portion of the region 131-158 of myelin basic protein. In particular, there is provided an apitope which is selected from the following myelin basic protein peptides: 134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140-154. There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.
申请公布号 PL212129(B1) 申请公布日期 2012.08.31
申请号 PL20030371549 申请日期 2003.01.30
申请人 APITOPE TECHNOLOGY (BRISTOL) LIMITED 发明人 WRAITH DAVID CAMERON;STREETER HEATHER BARBARA;PONSFORD FRANCES MARY;MAZZA GRAZIELLA
分类号 A61K38/00;C07K14/47;A61K38/04;A61K38/17;A61P25/00;A61P25/28;C07K7/08 主分类号 A61K38/00
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