发明名称 Novel cytostatic 7-deazapurine nucleosides
摘要 Disclosed are cytostatic 7-deazapurine nucleoside compounds of formula (I), wherein the variables R1 is furanyl, thienyl, pyrrolyl, thiazoyl, imidazolyl, pyridyl, selenophenyl, or pyrazolyl and R2 is as defined in the specification, and salts thereof, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds. These compounds are suitable for inhibiting cell proliferation in tumour/cancer cells in a subject and can be used for treating a cellular proliferation disease, a neoplastic disease or cancer.
申请公布号 NZ586610(A) 申请公布日期 2012.08.31
申请号 NZ20090586610 申请日期 2009.01.15
申请人 INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR, V.V.I. 发明人 HOCEK, MICHAL;NAUS, PETR
分类号 C07H19/14;A61K31/7064 主分类号 C07H19/14
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