PURPOSE: A method for coating heparin on the surface of a stent is provided to maintain a blood clot coagulation effect by improving heparin attachment stability. CONSTITUTION: A method for coating heparin on the surface of a stent is as follows. A coating solution is prepared by adding EDC(1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride) and NHS(N-hydroxysulfosuccinimide) to a mixture solution of heparin and dopamine. A metal stent is dipped in the coating solution. The metal stent is made of a material selected from a group consisting of stainless steel, Co-Cr alloy, tantalum, and gold.
申请公布号
KR101178793(B1)
申请公布日期
2012.08.31
申请号
KR20110027886
申请日期
2011.03.29
申请人
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;CHONNAM NATIONAL UNIVERSITY HOSPITAL
发明人
BAE, IN HO;CHO, EUN JEONG;PARK, IN KYU;KIM, DONG GON;JEONG, MYUNG HO;KIM, JU HAN;HAN, DONG KEUN;CHO, SANG KI