Method for producing an intermediate product of dabigatran etexilate
摘要
Disclosed is a process for synthesising the amidine benzimidazole derivative of formula 1, comprising reacting a diamine with an oxadiazolone, then without isolating the product, converting it to the amidine of formula 1, where the diamine and oxadiazolone have the structures given in the specification.
申请公布号
NZ588488(A)
申请公布日期
2012.08.31
申请号
NZ20090588488
申请日期
2009.06.12
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人
FILSER, CHRISTIAN;DERSCH, WOLFGANG;HAMM, RAINER;HAUSHERR, ARNDT;KOCH, GUNTER;SCHOLZ, ULRICH;ZERBAN, GEORG