发明名称 COMPOSITIONS FOR REDUCING GASTRO-INTESTINAL METHANOGENESIS IN RUMINANTS
摘要 The present invention concerns the reduction of gastro-intestinal methanogenesis in ruminants with the aid of agents that compete for the hydrogen atoms required by methanogens during normal fermentation of ingested feed. The invention in one aspect resides in the findings that both nitrate reductive pathways as well as sulphate reductive pathways outcompete gastro-intestinal methanogenesis in ruminants and, that the methanogenesis reducing effects of nitrate and sulphate are completely additive. At the same time the combined administration of nitrate and sulphate was found to be fully effective to avoid or mitigate the potential problems of nitrite intoxication normally encountered when using nitrate alone, which effect is further enhanced, where necessary, by the addition of a nitrite reducing probiotic micoroorganism. Hence, products are provided comprising high amounts of a combination of a nitrate compound and a sulphate compound and optionally a nitrite reducing probiotic microorganism, as well as methods of reducing gastro-intestinal methanogenesis in ruminants using such compositions.
申请公布号 US2012219527(A1) 申请公布日期 2012.08.30
申请号 US201013386368 申请日期 2010.07.23
申请人 PERDOK HINDRIK BENE;VAN ZIJDERVELD SANDER MARTIJN;NEWBOLD JOHN RICHARD;HULSHOF ROB BERNARD ANTON;DESWYSEN DAVID;GERRITS WALTER JAN JOZEF;DIJKSTRA JAN;LENG RONALD ALFRED;PROVIMI HOLDING B. V. 发明人 PERDOK HINDRIK BENE;VAN ZIJDERVELD SANDER MARTIJN;NEWBOLD JOHN RICHARD;HULSHOF ROB BERNARD ANTON;DESWYSEN DAVID;GERRITS WALTER JAN JOZEF;DIJKSTRA JAN;LENG RONALD ALFRED
分类号 A61K35/74;A61K33/04;A61K35/66;A61P1/00;A61P3/02 主分类号 A61K35/74
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