MULTI-LAYERED PERMEATION DEVICE

摘要

PROBLEM TO BE SOLVED: To provide a simple improved multi-layered permeation device (1) which can supply the first active agent in an outer layer (2) to one use environment and supply the second active agent in a core (5) to another use environment.

SOLUTION: A permeation device is provided, in which the first and second active agents are identical to or different from each other. A leachable polymer coating (3), between an inner semi-permeable membrane (4) and an outer coating (2) containing the second active agent, contains poly(vinylpyrrolidone)-(vinyl acetate) copolymer. An improved multi-layered permeation device having an advantage exceeding related devices known in the field is obtained with the specific leachable polymer. An active agent in a core (5) is supplied through pores (6) including a leachable plug (7). The permeation device (1) can be coated with a final finishing coating (8).

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