NOVEL 3-HYDROXY-5-ARYLISOTHIAZOLE DERIVATIVE

摘要

[Problem]To provide a GPR40 activating agent having, as an active ingredient, a novel compoundhaving a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin seaetagogue and a prophylactic and/ortherapeutic agent against diabetes, obesity, or other diseases.[Means of solving the problem] A compound of Formula (I).[err](where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl groupwhich is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is 0, S, -NR-7-; and Rt to R7 are specific groups),a salt of the compound, or a solvate of the salt or the compound.No Suitable Figure