发明名称 |
PREDICTING TOXICITY OF A COMPOUND OVER A RANGE OF CONCENTRATIONS |
摘要 |
A method of predicting hepatotoxicity of a compound. The method includes imaging cells of hepatic origin positioned within a plurality of containers to obtain imaged cellular targets, each container being treated with a different concentration of the compound, the imaging being performed using a quantitative high-content cell imaging system; quantitatively measuring the imaged cellular targets to detect changes in multiple cellular targets associated with cytotoxicity of the compound; and analyzing measurements obtained from the measured imaged cellular targets over a range of compound concentrations to determine the hepatotoxicity of the compound.
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申请公布号 |
US2012219204(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
US201213402219 |
申请日期 |
2012.02.22 |
申请人 |
HONG SUK JIN;GHOSH RICHIK NILOY;CELLOMICS, INC. |
发明人 |
HONG SUK JIN;GHOSH RICHIK NILOY |
分类号 |
G06K9/00 |
主分类号 |
G06K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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