| 摘要 |
P OPER/1AL12M9007%892 Div doc- 16,6,219 The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids 5 for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments comprising one or more cannabinoids via mucosal surfaces, comprising: at least one lipophilic medicament which comprises one or 10 more cannabinoids, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55 % wt/wt of the formulation, the formulation is absent of a self emulsifying agent and/or a fluorinated propellant, and the cannabinoid(s) is/are 15 present in the formulation in an amount greater than 10 mg/ml. |
