发明名称 |
USE OF VECTORS EXPRESSING INTRACELLULAR POLYNUCLEOTIDE BINDING PROTEINS AS ADJUVANTS |
摘要 |
An object of the invention is to provide a vaccine adjuvant that is comprised of a vector capable of expressing a polynucleotide binding protein in excess of levels already present in cells. Expression of the polynucleotide binding protein initiates intracellular pathways that lead to expression of type 1 interferons. In concert with expression of type 1 interferons, other cytokines are expressed, and the immune response to vaccine antigens given with the adjuvant is enhanced. |
申请公布号 |
US2012219591(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
US200913138869 |
申请日期 |
2009.10.22 |
申请人 |
LJUNGBERG KARL;LLADSER ALVARO;KIESSLING ROLF |
发明人 |
LJUNGBERG KARL;LLADSER ALVARO;KIESSLING ROLF |
分类号 |
A61K39/00;A61P37/04 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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