发明名称 |
RECOMBINANT MUMPS VIRUS VACCINE |
摘要 |
The present invention provides the complete genomic sequence of the epidemic mumps virus (MuV) strain MuVIowa/us/06. Further, a reverse genetics system was constructed and used to rescue recombinant viral constructs that are attenuated compared to MuVIowa/us/06 and JL vaccine viruses. Such constructs include viral constructs lacking the open reading frame (ORF) of the SH gene (rMuV?SH) and/or incapable of expressing the V protein (rMuV?V). |
申请公布号 |
CA2828229(A1) |
申请公布日期 |
2012.08.30 |
申请号 |
CA20122828229 |
申请日期 |
2012.02.24 |
申请人 |
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. |
发明人 |
HE, BIAO |
分类号 |
A61K48/00;A61K38/08;A61P31/00;A61P31/12 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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