发明名称 Methods of Treating Hormone-Related Conditions Using Thio-Oxindole Derivatives
摘要 The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I, or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula I is: and wherein R1-R5 and Q1 are defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I and a selective estrogen receptor modulator are also described.
申请公布号 US2012220558(A1) 申请公布日期 2012.08.30
申请号 US201213466375 申请日期 2012.05.08
申请人 WYETH LLC 发明人 FENSOME ANDREW;GRUBB GARY S.;HARRISON DIANE DEBORAH;WINNEKER RICHARD CRAIG
分类号 A61K31/404;C07D403/04;A61K31/138;A61K31/353;A61K31/40;A61K31/4025;A61K31/4535;A61K31/454;A61K31/55;A61K31/567;A61K45/00;A61K45/06;A61P1/00;A61P5/24;A61P7/04;A61P11/00;A61P13/08;A61P15/00;A61P15/12;A61P15/18;A61P35/00 主分类号 A61K31/404
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