发明名称 PROLINE DERIVATIVES AND THEIR USE AS DIPEPTIDYL PEPTIDASE IV INHIBITORS
摘要 The invention provides compounds of formula (I), prodrugs and stereoisomers thereof, and the pharmaceutically acceptable salts of the compounds, prodrugs, and stereoisomers, wherein R, R, R, HET, n, Q, X, Y, and Z are as described herein; compositions thereof; and uses thereof in treating diabetic complications including diabetic neuropathy, diabetic nephropathy, diabetic microangiopathy, and the like.
申请公布号 EA011086(B9) 申请公布日期 2012.08.30
申请号 EA20060001896 申请日期 2005.04.29
申请人 PFIZER PRODUCTS INC. 发明人 HULIN BERNARD;PIOTROWSKI DAVID, WALTER
分类号 C07D403/14;A61K31/496;A61P3/10;C07D207/14;C07D235/00;C07D241/00;C07D249/00;C07D401/14;C07D403/06;C07D413/14;C07D417/14;C07D487/02;C07D487/04;C07D487/14;C07D498/04 主分类号 C07D403/14
代理机构 代理人
主权项
地址