| 摘要 |
Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension. |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
ANAND, RAJAN;APGAR, JAMES M.;BIFTU, TESFAYE;CHEN, PING;CHU, LIN;COLANDREA, VINCENT J.;DONG, GUIZHEN;DROPINSKI, JAMES F.;FENG, DANQING;HICKS, JACQUELINE D.;JIANG, JINLONG;KIM, ALEXANDER J.;LEAVITT, KENNETH J.;LI, BING;QIAN, XIAOXIA;SEBHAT, IYASSU;WEI, LAN;WILKENING, ROBERT R.;WU, ZHICAI |
