发明名称 COMPOSITIONS AND METHODS FOR CONTROLLING PUPIL DILATION COMPRISING PHENTOLAMINE
摘要 The disclosure provides a composition for controlling pupil dilation comprising about 0.001% to about 1.0% by weight of an alpha-adrenergic receptor antagonist selected from phentolamine, phentolamine mesylate, or a phentolamine salt; and at least one excipient selected from the group consisting of a buffer, tonicity agent, preservative, antioxidant, surfactant, solubilizer, cosolvent, and a combination thereof. A method of controlling pupil dilation in a subject in need thereof, comprising administering a therapeutically effective amount of the composition is also provided.
申请公布号 EP2490668(A1) 申请公布日期 2012.08.29
申请号 EP20100773774 申请日期 2010.10.20
申请人 ALLERGAN, INC. 发明人 LIKITLERSUANG, SUKHON;PARASHAR, AJAY P.;PUJARA, CHETAN P.
分类号 A61K9/00;A61K31/417;A61K47/00 主分类号 A61K9/00
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