发明名称 |
ISLET CELL SHEET, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF |
摘要 |
A polymer that changes hydration at a temperature between 0 to 80°C is coated on the surface of a cell culture support, and islet cells are cultured on the support at a temperature range that causes polymer to have weak hydration, then the temperature of a culture solution is changed to a temperature that causes the polymer to have strong hydration to obtain islet cells in a sheet form. Such islet cells in a sheet form have an insulin producing function even if there is no blood flow. |
申请公布号 |
EP2491957(A1) |
申请公布日期 |
2012.08.29 |
申请号 |
EP20100806422 |
申请日期 |
2010.08.02 |
申请人 |
TOKYO WOMEN'S MEDICAL UNIVERSITY |
发明人 |
SHIMIZU, HIROFUMI;OHASHI, KAZUO;YAMADA, RIE;ISE, KAZUYA;YAMATO, MASAYUKI;OKANO, TERUO;GOTOH, MITSUKAZU |
分类号 |
A61L27/36;A61L27/38;C12N5/071 |
主分类号 |
A61L27/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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