发明名称 |
PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE |
摘要 |
The present invention is to provide a process for simply producing an optically active 3-hydroxypropionic ester derivative useful as a medicament intermediate from an inexpensive material. More specifically, the present invention is directed to a process for producing an optically active 3-hydroxypropionic ester derivative comprising reacting an acetic ester derivative available at low cost with a base and a formic ester, thereby converting the acetic ester derivative into a 2-formylacetic ester derivative, and thereafter, stereospecifically reducing the formyl group of the derivative by use of an enzymatic source capable of stereoselectively reducing the formyl group of the derivative. |
申请公布号 |
EP1568679(A4) |
申请公布日期 |
2012.08.29 |
申请号 |
EP20030777330 |
申请日期 |
2003.12.08 |
申请人 |
KANEKA CORPORATION |
发明人 |
TAOKA, NAOAKI;MORIYAMA, DAISUKE;MORI, KOHEI;OISHI, TAKAHIRO |
分类号 |
C07C67/36;C07C67/313;C07C69/716;C07D317/60;C12P7/62;C12P17/04;C12P41/00 |
主分类号 |
C07C67/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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