发明名称 Piperidinyl and piperazinyl modulators of γ-secretase
摘要 The present invention relates to compounds of Formula I as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
申请公布号 US8252935(B2) 申请公布日期 2012.08.28
申请号 US20080251521 申请日期 2008.10.15
申请人 HO CHIH YUNG;ZHANG YAN;MAHAROOF UMAR S. M.;MAJOR JEREMY;HARRISON JOHN;JANSSEN PHARMACEUTICA N.V.;CELLZOME LIMITED 发明人 HO CHIH YUNG;ZHANG YAN;MAHAROOF UMAR S. M.;MAJOR JEREMY;HARRISON JOHN
分类号 C07D211/08;A61K31/445;A61K31/497;C07D237/00 主分类号 C07D211/08
代理机构 代理人
主权项
地址