CELL PROTECTING COMPOSITION FOR TOXICITY SUPPRESSION OF NATURAL KILLER CELL COMPRISING RETINAL OR RETINOIC ACID AS AN EFFECTIVE COMPONENT
摘要
PURPOSE: A cytoprotection composition for toxicity suppression of natural killer cells including retinal or retinoic acid are provided to reduce or suppress toxicity of the natural killer cells by including T-cells. CONSTITUTION: A cytoprotection composition for toxicity suppression of natural killer cells includes retinal or retinoic acid as an active ingredient. The retinal or retinoic acid suppresses or prevent the cytotoxin of the natural killer cell as reduction. 0.1-5 microM of the retinal or retinoic acid is included. The cytoprotection composition for toxicity suppression of natural killer cells comprises T-cells which are differentiated by processing the retinal or the retinoic acid and human adipose derived mesenchymal stem cells. The differentiated Thymusdependentlymphocyte(treg cell) and the human adipose derived mesenchymal stem cells are included at a rate of 1:0.01-1:0.03.
申请公布号
KR20120095320(A)
申请公布日期
2012.08.28
申请号
KR20120016400
申请日期
2012.02.17
申请人
CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATIONFOUNDATION
发明人
CHO, MI LA;CHO, SEOK GOO;PARK, MIN JUNG;LIM, JUNG YEON;LEE, SUNG HEE;LIM, GUN IL