发明名称 |
STEREOSELECTIVE 3,4-DIMETHYLENEOXEPANE COMPOUNDS SUBSTITUTED AND PROCESS FOR PREPARING THEM |
摘要 |
PURPOSE: A stereoselectivity 3,4-die methylene jade force pane compound and a manufacturing method thereof are provided to be useful as intermediate which synthesizes the various multicyclic compounds. CONSTITUTION: A stereoselectivity 3,4-die methylene jade force pane compound is represented by chemical formula 1. A manufacturing method of the 3,4-die methylene jade force pane compound comprises the following step: performing Prins cyclization of solvents selected from diethyl ether and tetrahydrofuran under existence of trimethylsilyl trifluoro methansulfonate(TMSOTf) or tin tetrachloride(TiCl4) using aldehyde compound represented by chemical formula 3 as a starting material. The manufacturing method uses 1-2 equivalent weight range of Lewis acid based the alcoholates represented. The Prins reaction temperature is in a range of -78-30 deg. Celsius.
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申请公布号 |
KR20120095252(A) |
申请公布日期 |
2012.08.28 |
申请号 |
KR20110014803 |
申请日期 |
2011.02.18 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
CHO, YONG SEO;MIN, SUN JOON;LEE, JAE KYUN;PAE, AE NIM;ULLAPU PUNNA REDDY |
分类号 |
C07D313/04;C07D407/04;C07D409/04 |
主分类号 |
C07D313/04 |
代理机构 |
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