TRANSDERMAL DELIVERY DEVICES ASSURING AN IMPROVED RELEASE OF AN ACTIVE PRINCIPLE THROUGH A BIOLOGICAL INTERFACE

摘要

A transdermal drag delivery system is provided for passive transdermal delivery of one or more ionizable active agents to a biological interface of a subject. A transdermal drug delivery system includes a backing substrate, and an active agent layer. The active layer includes a thickening agent, a plasticizer, and a therapeutically effective amount of an ionizable active agent.