METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES
摘要
Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.
申请公布号
CA2827679(A1)
申请公布日期
2012.08.23
申请号
CA20122827679
申请日期
2012.02.17
申请人
ALEXION PHARMA INTERNATIONAL SARL
发明人
LONG, XIANGTIAN;DAI, DANMEI;BRUNNER, ANDREAS;WATT, DEREK KEVIN;CLINCH, KEITH;BAARS, SYLVIA MYRNA;DIXON, RACHEL ANNE;LITTLE, GILLIAN MARY;LANDREAU, CYRILLE ABEL SEBASTIEN;PROISY, NICOLAS GEORGES RENE