| 发明名称 |
ISOLATED PON1 POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME AND USES THEREOF IN TREATING OR PREVENTING ORGANOPHOSPHATE EXPOSURE ASSOCIATED DAMAGE |
| 摘要 |
An isolated polypeptide comprising the amino acid sequence of serum paraoxonase (PON1) having catalytic efficiency of kcat/KM≈106-5·107 M−1min−1 for a G-type organophosphate.
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| 申请公布号 |
US2012213834(A1) |
申请公布日期 |
2012.08.23 |
| 申请号 |
US201213420920 |
申请日期 |
2012.03.15 |
| 申请人 |
TAWFIK DAN S.;GUPTA RINKOO DEVI;GOLDSMITH MOSHE;ASHANI YAACOV;YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
TAWFIK DAN S.;GUPTA RINKOO DEVI;GOLDSMITH MOSHE;ASHANI YAACOV |
| 分类号 |
A61K38/46;A61K9/00;A61P43/00;C12N9/16;C12N15/55;C12N15/63 |
主分类号 |
A61K38/46 |
| 代理机构 |
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代理人 |
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