发明名称 FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS.
摘要 <p>Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, L1, L2, R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.</p>
申请公布号 MX2012007402(A) 申请公布日期 2012.08.23
申请号 MX20120007402 申请日期 2010.12.17
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 CHRISTOPHER SMITH;MASASHI TAKAHASHI;BENJAMIN JONES;VICTORIA FEHER;BETTY LAM;ZHE NIE;YASUYOSHI ARIKAWA;QING DONG
分类号 C07D471/04;A61K31/437;A61K31/519;A61P7/00;A61P11/00;A61P17/00;A61P19/00;A61P29/00;A61P35/00;A61P37/00;C07D487/04 主分类号 C07D471/04
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